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Doron D. Kahana, MD, CPNS, Khalid M. Khan, MD, "Jaundice", Berkowitz’s Pediatrics: A Primary Care Approach, Carol D. Berkowitz, MD, FAAP
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Jaundice occurs when bilirubin reaches a level in the blood that makes it visibly apparent. In newborns, this level is 5 mg/dL. In older children and adolescents, jaundice becomes apparent at serum bilirubin levels of 2 mg/dL. The term physiologic jaundice is used to denote the jaundice that normally occurs after birth. In full-term neonates, bilirubin reaches its peak of approximately 6 mg/dL between the second and fourth days after birth. Levels above 10 mg/dL likely are not physiologic. Typically, bilirubin returns to a normal level (≤1 mg/dL) by 12 days of age. Preterm newborns experience their peak level of...
