Youths who are negatively affected by social determinants of health suffer adverse effects like increased risks of chronic health conditions and mental health issues. Part 3 of this series describes ways pediatricians can help fight these social determinants to promote health equity for our most vulnerable children. Available for purchase at https://www.aap.org/Pediatric-Collections-Social-Determinants-of-Health-Part-3-Promoting-Health-Equity-Paperback