Developed by top pediatric hospitalists, Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, 3rd Edition, is sure to become your go-to resource from initial patient evaluation all the way through discharge management. Quickly obtain the essential information for managing a wide range of pediatric medical conditions in patients who have been admitted to the hospital with this trusted, pocket-sized reference. Available for purchase at https://www.aap.org/caring-for-the-hospitalized-child-a-handbook-of-inpatient-pediatrics-3rd-edition-paperback/
4: Anaphylaxis
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Published:May 2023
Kara Ditlevson-Smith, DO, FAAP, Stephanie Jennings, MD, "Anaphylaxis", Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, American Academy of Pediatrics Section on Hospital Medicine, Jeffrey C. Gershel, MD, FAAP, Daniel A. Rauch, MD, FAAP, SFHM
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The term anaphylaxis applies to anaphylactic (immunoglobulin E [IgE]–mediated) and anaphylactoid (non–IgE-mediated) release of immune mediators from basophils and mast cells. It is a severe, potentially fatal, systemic allergic reaction. Therefore, it is imperative to recognize the signs and symptoms of anaphylaxis and treat it rapidly. The most common triggers are peanuts, tree nuts, and shellfish, although anaphylaxis in an inpatient may be triggered by exposure to latex, radiocontrast material, medications, or foods (Table 4–1).
As many as 15% to 20% of patients will have a biphasic response, with most episodes occurring within 6 to 12 hours after...
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