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15: Erythema Multiforme, Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis, and Mycoplasma Pneumonia-Induced Rash and Mucositis
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Published:May 2023
Laurie Bernard Stover, MD, "Erythema Multiforme, Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis, and Mycoplasma Pneumonia-Induced Rash and Mucositis", Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, American Academy of Pediatrics Section on Hospital Medicine, Jeffrey C. Gershel, MD, FAAP, Daniel A. Rauch, MD, FAAP, SFHM
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Erythema multiforme (EM), Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), and Mycoplasma-induced rash and mucositis (MIRM) are relatively uncommon, distinct disorders of the skin and mucous membranes. Classic EM involves the skin only, whereas SJS/TEN always affects the skin and mucous membranes. MIRM is now the proper terminology when a Mycoplasma infection causes a mucocutaneous eruption, as the clinical features are distinct from SJS/TEN. MIRM always involves the mucous membranes and may occur with or without skin involvement. EM is thought to be a postinfectious process, with herpes simplex virus (HSV) being the most well-documented trigger. Both SJS and TEN...
