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16: Rashes Associated with Serious Underlying Disease
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Published:May 2023
Laurie Gordon, MA, MD, FAAP, "Rashes Associated with Serious Underlying Disease", Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, American Academy of Pediatrics Section on Hospital Medicine, Jeffrey C. Gershel, MD, FAAP, Daniel A. Rauch, MD, FAAP, SFHM
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Rashes associated with acute illnesses are common in children. However, there are a few that can be associated with serious diseases that can have significant morbidity and mortality. These include erythroderma, some cases of cellulitis, petechiae/purpura, target lesions, and vesicles/bullae.
Obtain a thorough description of the evolution of the rash. Determine when and where it started, the initial appearance and any change, and the pattern of spread (eg, from head to trunk or from hands to trunk). Note if the rash is painful or pruritic.
Ask about associated symptoms, such as the duration and intensity of any fever, fatigue, irritability,...
