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Orbital (postseptal) cellulitis and periorbital (preseptal) cellulitis are major infections of the orbital tissues. Periorbital cellulitis is a superficial infection, whereas orbital cellulitis involves deeper structures behind the orbital septum. Orbital cellulitis is an ocular emergency as it is associated with significant morbidity and mortality, including intracranial extension of infection in up to 5% of patients.

The orbital septum is a tough, fibrous membrane that runs from the periosteum of the orbital bones to the tarsal plates. It functions as a barrier between the superficial skin/subcutaneous tissues of the periorbital space and the deep intraorbital structures, preventing superficial (ie, periorbital/preseptal)...

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