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Hyperthyroidism is rare in children, but if unrecognized, it can have potentially fatal consequences. The most common cause (95%) of hyperthyroidism in pediatrics is Graves disease (autoimmune hyperthyroidism), which primarily affects female adolescents. There is a strong genetic predilection and association with other autoimmune diseases within the family or in the same patient. Other causes of hyperthyroidism include pituitary and thyroid adenomas, Hashitoxicosis, suppurative or subacute viral thyroiditis, and drug-induced (amiodarone, iodine) thyrotoxicosis.

Thyroid storm, or thyrotoxic crisis, is a rare, multisystem medical emergency that may be precipitated by acute illness, surgery, or abrupt withdrawal of antithyroid medications in a...

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