Developed by top pediatric hospitalists, Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, 3rd Edition, is sure to become your go-to resource from initial patient evaluation all the way through discharge management. Quickly obtain the essential information for managing a wide range of pediatric medical conditions in patients who have been admitted to the hospital with this trusted, pocket-sized reference. Available for purchase at https://www.aap.org/caring-for-the-hospitalized-child-a-handbook-of-inpatient-pediatrics-3rd-edition-paperback/
60: Systemic Lupus Erythematosus
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Published:May 2023
Jennifer Fuchs, MD, FAAP, Mary Esther M. Rocha, MD, MPH, FAAP, "Systemic Lupus Erythematosus", Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, American Academy of Pediatrics Section on Hospital Medicine, Jeffrey C. Gershel, MD, FAAP, Daniel A. Rauch, MD, FAAP, SFHM
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Systemic lupus erythematosus (SLE) is a chronic, multisystem, autoimmune disease characterized by episodic periods of increased systemic inflammation known as “flares.” Up to 20% of SLE cases are diagnosed before 18 years of age (ie, childhood SLE [cSLE]). The mean age of onset of cSLE is 11 to 12 years, with few cases in children under 5 years of age. There is a female predominance in childhood (3:1), which triples during puberty (9:1). Due to a higher prevalence of complications within the first 2 years of illness, cSLE has higher morbidity and mortality than adult-onset SLE (aSLE).
The most common...
