Developed by top pediatric hospitalists, Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, 3rd Edition, is sure to become your go-to resource from initial patient evaluation all the way through discharge management. Quickly obtain the essential information for managing a wide range of pediatric medical conditions in patients who have been admitted to the hospital with this trusted, pocket-sized reference. Available for purchase at https://www.aap.org/caring-for-the-hospitalized-child-a-handbook-of-inpatient-pediatrics-3rd-edition-paperback/
65: Multisystem Inflammatory Syndrome in Children (Mis-C)
-
Published:May 2023
Edward E. Conway, Jr, MD, FAAP, FCCM, "Multisystem Inflammatory Syndrome in Children (Mis-C)", Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, American Academy of Pediatrics Section on Hospital Medicine, Jeffrey C. Gershel, MD, FAAP, Daniel A. Rauch, MD, FAAP, SFHM
Download citation file:
Initial reports from the COVID-19 pandemic suggested that children were less susceptible to the disease. Subsequently, a severe and novel pediatric disorder, termed multisystem inflammatory syndrome in children (MIS-C), was described. Although the exact pathophysiology is currently unknown, the temporal relationship of MIS-C to acute COVID-19 disease suggests that the pathogenesis involves postinfectious immune dysregulation with an exaggerated immune response, leading to cytokine storm and hyperinflammation in multiple organs.
Most patients with MIS-C have had a prior infection with, or an exposure to, someone with acute COVID-19 disease in the 2 to 4 weeks prior to developing signs and symptoms....
