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Children and youth are exposed to large number of potentially toxic substances. This has a major impact on child health, especially among children living in poverty. In 2020, 58% of calls to poison control centers and 7% of toxin-related fatalities involved patients younger than 20 years. Younger patients (< 6 years) have better outcomes because they usually present promptly to a health care facility, have fewer comorbid conditions, are exposed to a single substance, and are not trying to harm themselves. However, some substances are potentially fatal in small doses (Box 68–1).

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