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71: Acute Glomerulonephritis
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Published:May 2023
Vivian Lee, MD, FAAP, Jennifer Maniscalco, MD, MPH, MAcM, FAAP, "Acute Glomerulonephritis", Caring for the Hospitalized Child: A Handbook of Inpatient Pediatrics, American Academy of Pediatrics Section on Hospital Medicine, Jeffrey C. Gershel, MD, FAAP, Daniel A. Rauch, MD, FAAP, SFHM
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The term acute glomerulonephritis (AGN) encompasses the spectrum of diseases that lead to variable degrees of inflammation in the glomeruli. It can be an isolated, self-limited illness or the first presentation of chronic glomerulonephritis (GN). Clinical manifestations can vary from asymptomatic microscopic hematuria to acute nephritic syndrome, characterized by abrupt onset of gross hematuria, proteinuria, and edema, often with hypertension and some degree of renal insufficiency.
Postinfectious AGN (PIAGN) is the classic example of AGN and the most frequent cause in children. It most commonly occurs after a pharyngitis or skin infection with group A Streptococcus, although it can...
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