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Urinary tract infections (UTIs) may involve the lower (cystitis) or the upper tract (pyelonephritis). Distinguishing between the two, particularly in a patient younger than 2 years, can be difficult. Patients at higher risk for pyelonephritis include infants younger than 6 months, females, uncircumcised males, and children with underlying obstructive urologic abnormalities or bladder and bowel dysfunction.

An infant or young child may present with fever and nonspecific symptoms, such as poor weight gain, lethargy or irritability, vomiting, diarrhea, or poor feeding. An older child or adolescent will report fever, urinary problems (eg, dysuria, urinary frequency, incontinence, hematuria), or abdominal/back pain....

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