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A brief resolved unexplained event (BRUE) is defined as an incident that occurs in an infant younger than 1 year, when the observer reports a sudden, brief, and resolved episode of one or more of the following: cyanosis or pallor; absent, decreased, or irregular breathing; marked change in tone (hyper- or hypotonia); and altered level of responsiveness. A BRUE is a diagnosis of exclusion, assigned when there is no explanation for a qualifying event after compiling an appropriate history and conducting a physical examination.

It is important to note that, unlike the previously used term apparent life-threatening event, a...

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