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Pyloric stenosis is the most common cause of upper gastrointestinal (UGI) obstruction in infancy, with an incidence of 2 to 4 per 1,000 live births. Male infants are 4 to 6 times more likely to be affected, with 30% of patients being first-born males. With prompt diagnosis and intervention, pyloromyotomy can prevent complications such as significant metabolic derangements, failure to thrive (FTT), shock, and death (rare).

The patient typically presents at 10 days to 8 weeks after birth, with progressively forceful, nonbilious emesis after feedings. The vomiting may be described as projectile and is nonbilious and nonbloody.

Depending on the...

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