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Bronchiolitis usually manifests as an isolated episode, mostly a viral lower respiratory tract infection in an infant with symptomatic airway obstruction. Most patients are younger than 1 year; however, bronchiolitis can occur beyond infancy. It is characterized by acute inflammation, edema and necrosis of the epithelial lining of small airways, and mucus production. An infant with bronchiolitis typically presents with increased work of breathing manifested by retractions and associated with polyphonic wheeze, which may be heard without a stethoscope.

As many as 3% of all US infants are hospitalized annually for bronchiolitis, making this clinical problem the leading cause of...

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