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Sickle cell disease (SCD) affects approximately 100,000 individuals in the United States and is the most common inherited disorder among African Americans.1  Because a large number of people with SCD are from vulnerable populations (including communities of color and largely uninsured and underinsured individuals), striking disparities exist in research and clinical care for SCD in comparison to other inherited diseases, such as cystic fibrosis.2  There have been advances in recent decades regarding diagnosis, preventive management, and treatment for SCD—all of which have led to improved survival for children3 —however, the median life expectancy is in the fifth...

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