Completely revised and updated, the second edition of this authoritative guide provides the latest information on the diagnosis, treatment, and ongoing management of pulmonary issues in children. Available for purchase at https://www.aap.org/Pediatric-Pulmonology-2nd-Edition-Paperback
53: Pulmonary Complications of Immunologic Disorders
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Published:November 2023
Jay Jin, MD, PhD, Clement L. Ren, MD, MBA, "Pulmonary Complications of Immunologic Disorders", Pediatric Pulmonology, American Academy of Pediatrics Section on Pediatric Pulmonology and Sleep Medicine, Michael J. Light, MD, FAAP, Kristin Van Hook, MD, MPH, FAAP
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The respiratory tract is continuously exposed to pathogens through inhalation. To protect against infection, the lungs have a variety of defense mechanisms, including a mucociliary barrier, the innate immune system, and the adaptive immune system. This chapter focuses on pulmonary complications arising from congenital and acquired defects in innate and adaptive immunity. This chapter does not address the diagnostic workup of suspected immunologic conditions, which should be undertaken in collaboration with an experienced immunologist.
Each component of the immune system serves a specific role in host defense. A deficiency in any one element of the immune system renders individuals susceptible...
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