Completely revised and updated, the second edition of this authoritative guide provides the latest information on the diagnosis, treatment, and ongoing management of pulmonary issues in children. Available for purchase at https://www.aap.org/Pediatric-Pulmonology-2nd-Edition-Paperback
56: Aerosol Delivery of Medication
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Published:November 2023
Ariel Berlinski, MD, FAAP, FAARC, "Aerosol Delivery of Medication", Pediatric Pulmonology, American Academy of Pediatrics Section on Pediatric Pulmonology and Sleep Medicine, Michael J. Light, MD, FAAP, Kristin Van Hook, MD, MPH, FAAP
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Inhaled therapy is a mainstay of treatment for a wide variety of respiratory diseases in children. Disease management guidelines recommend inhaled corticosteroids and bronchodilators for controlling asthma, and mucoactive agents and antibiotics for treatment of lung disease in cystic fibrosis (CF).1,2 There is also interest in using aerosols for systemic delivery of molecules that would otherwise be degraded in the gut or require injection.
The challenges of successful delivery of drugs to the lungs are much greater than those of either oral or systemic drug delivery. The respiratory tract is efficient at filtering out foreign materials. Aerosol...
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