Source:

Dong
Y
,
Stallmann-Jorgensen
IS
,
Pollock
NK
, et al
.
A 16- week randomized clinical trial of 2000 international units daily vitamin D3 supplementation in black youth: 25-hydroxyvitamin D, adiposity and arterial stiffness
.
J Clin Endocrinol Metab.
2010
;
95
(
10
):
4584
-
4591
; doi:
https://doi.org/10.1210/jc2010-0606
.

Investigators at the Medical College of Georgia and Boston University Medical Center endeavored to assess 25(OH) D concentrations in response to 2,000 IU vitamin D supplementation over time; evaluate whether 2,000 IU achieves optimal vitamin D status; determine the relationship between adiposity and 25(OH)D concentrations; and measure the effect of vitamin D supplementation on arterial stiffness measured by pulse wave velocity (PWV).

Forty-nine African American adolescents (16.3 ± 1.4 years) were randomly assigned to either a control group (400 IU/day D3) or an experimental group (2,000 IU/day D3) over a 16-week period. Compliance (pill...

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