Source:

Piske
M
,
Homayra
F
,
Min
JE
, et al
.
Opioid use disorder and perinatal outcomes
.
Pediatrics
.
2021
;
148
(
4
):
e2021050279
. doi:
https://doi.org/10.1542/peds.2021-050279

Investigators from multiple institutions in Canada conducted a retrospective study to evaluate perinatal outcomes in infants born to mothers with opioid use disorder (OUD). For the study, they linked multiple databases to identify mothers with OUD diagnosed before delivery or in the puerperium period with completed pregnancies between April 1, 2000 and March 31, 2019 in British Columbia, Canada. Data abstracted on mothers included age, parity, gestational age, receipt of opioid agonist treatment, timing of treatment (before pregnancy, during pregnancy but not until delivery, or until delivery), type of opioid agonist treatment (methadone, slow release oral morphine [SROM], buprenorphine/naloxone), use of other psychotropic drugs during pregnancy (selective serotonin reuptake inhibitors [SSRIs], benzodiazepines, antipsychotics, and stimulants), tobacco...

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