British researchers found no evidence measles, mumps and rubella (MMR) vaccine causes autism in children.
The authors undertook a population-based study to investigate trends in the incidence of autistic disorders before and after the introduction of MMR vaccine in October 1988. Previous reports had suggested the vaccine was responsible for an increase in the incidence of autism.
Children with autistic disorders born after 1979 were identified using records from child development centers and special schools. Researchers verified the diagnosis by checking information in the records against criteria of the International Classification of Diseases, 10th revision. They also obtained immunization data for each child from a vaccine registry.