♦ Hopper SM, et al. Ann Emerg Med. Nov. 11, 2013.
Viscous lidocaine did not improve fluid intake among children with painful infectious mouth ulcers any better than flavored gel, according to a randomized, placebo-controlled study of 100 patients at a pediatric emergency department in Australia.
Children with ulcerative mouth conditions often get dehydrated because they do not drink enough. Pediatric experts have recommended using viscous lidocaine as a treatment, but little data exist on its efficacy.
This study assessed whether topical 2% viscous lidocaine is better than placebo at increasing fluid intake. A difference of 4 milliliters/kilogram (mL/kg) was considered clinically important.
Children ages 6 months to 8 years who were diagnosed with gingivostomatitis, ulcerative pharyngitis, herpangina, or hand, food and mouth disease and poor oral fluid intake were randomized to receive a single dose of 0.15 mL/kg of lidocaine or placebo. For the next 60 minutes, they...