Editor’s note:The following is reprinted from the March 2014 issue of AAP Grand Rounds. AAP News will publish select articles from this newsletter regularly. To access the full edition, go to aapgrandrounds.aappublications.org/.

Rowhani-Rahbar
A
, et al
“Effect of Age on the Risk of Fever and Seizures Following Immunization with Measles-containing Vaccines in Children.”
JAMA Pediatr
2013
;
167
:
1111
-1117
.

Investigators from multiple institutions used data from the Centers for Disease Control and Prevention-sponsored Vaccine Safety Datalink (VSD) to determine the effect of age on the risk of fever and seizures following administration of a measles-containing vaccine. All children who were 12 to 23 months of age and had received a measles-containing vaccine (measles, mumps and rubella [MMR] or measles, mumps, rubella and varicella [MMRV]) at one of eight VSD sites between 2001 and 2011 were included.

The primary outcomes were postimmunization...

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