♦ Poonai N, et al.CMAJ. 2014;186:1358-1363.

Ibuprofen was as effective as morphine in reducing pain in children with extremity fractures and was associated with fewer adverse events, according to a randomized study of 134 children ages 5-17 years treated in an emergency department (ED) in Ontario, Canada.

In 2013, the Food and Drug Administration required that a boxed warning be added to the labels of codeine-containing drugs after the deaths of children who had received codeine for pain relief following a tonsillectomy and/or adenoidectomy. Some data suggest that concerns over the safety of codeine has led to an increase in the use of orally administered morphine to control pain in children with injuries.

Ibuprofen, rather than morphine, should be the first-line outpatient treatment for children with acutely painful musculoskeletal trauma, according to the authors of a recent study.

The authors of this study sought to determine if morphine is...

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