Artificial insemination with donor semen is being used with increasing frequency for couples with male infertility and for some couples at high risk of having children with inherited diseases. It has been estimated that artificial insemination by donor other than husband currently results in 30,000 births annually in the United States.1 This accounts for approximately 1 percent of the 3 to 3.5 million babies born annually in this country.

The purpose of this commentary is to alert pediatricians to the increasing use of alternative reproductive methods, of which artificial insemination is the most frequent.

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