The Current Procedural Terminology instructions pertaining to immune globulin, vaccine, and toxoid codes (90281–90282, 90287–90399, 90476–90660, and 90665–90749) were revised to indicate that modifier 51 (multiple procedures) should not be appended to these codes. Given that these codes represent commodities and not services or procedures, they are not subject to multiple procedure reductions. A revision symbol () was added to the codes for which the modifier 51 exempt symbol (Ø) was removed. No changes were made to the descriptors of these codes.

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