Commentary by Alexandra K. Martinson, MD
Published February 2024

Cow’s milk protein allergy (CMPA) is the most common allergy among infants and young children. It is also the most common presentation for hematochezia in the neonate. General and specialty pediatricians across outpatient and inpatient settings have a role to play in the diagnosis and management of CMPA. From the presentation of the child with ongoing GI symptoms and growth faltering to managing food challenge trials and deciding on appropriate alternative formulas, pediatricians must have CMPA on the differential when caring for infants and toddlers and guiding parents in best feeding practices.

Keywords: food; hypersensitivity; enterocolitis syndrome; food allergy; milk allergy