Brief resolved unexplained events (BRUEs) are a common pediatric condition characterized by a change in color (cyanosis or pallor), breathing pattern, tone, or level of responsiveness in a child <1 year of age. For parents and caregivers, these events are frightening and warrant trying to identify an underlying cause. For pediatricians, BRUEs are a clinical challenge because the causes and long-term outcomes are not well understood despite decades of research. Despite these challenges and the limited evidence base, the American Academy of Pediatrics (AAP) published a clinical practice guideline (CPG) in 2016 to narrow the definition of BRUE and provide recommendations on management. Beyond retiring the term apparent life-threatening event for BRUE, the CPG outlined a revised risk stratification in which lower risk infants were defined as those >60 days of age, gestational age >32 weeks and postconceptional age >45 weeks, with no previous BRUEs, event duration <1...

You do not currently have access to this content.