Laryngomalacia is the most common cause of stridor in newborns. Affected patients may present with noisy breathing, a classic high-pitched inspiratory stridor that worsens with feeding. While the exact etiology remains unclear, the condition is characterized by softening of the supraglottic structures, including the epiglottis, aryepiglottic folds, and arytenoid cartilages. The condition is most often self-limited and requires expectant management. However, in some infants, severe disease, including failure to thrive or respiratory distress, may require medical or even surgical intervention. When caring for premature neonates, special care is required to evaluate for synchronous airway lesions.
Laryngomalacia in the Premature Neonate
Drs Leonard and Reilly have disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/investigative use of a commercial product/device.
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James A. Leonard, Brian K. Reilly; Laryngomalacia in the Premature Neonate. Neoreviews October 2021; 22 (10): e653–e659. https://doi.org/10.1542/neo.22-10-e653
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