A male neonate is born at 38 weeks’ gestation via elective cesarean section to a 28-year-old gravida 4, para 3 woman. The neonate’s parents are first-degree cousins without a significant family history. The maternal history is unremarkable. She received antenatal care at a polyclinic and the scan obtained at approximately 24 weeks’ gestation is normal. She presented to the emergency department at 36 weeks’ gestation with a history of decreased fetal movement and was later admitted to the labor and delivery unit for evaluation. The maternal laboratory findings are as follows: hepatitis B, negative; group B Streptococcus, negative; blood type, O positive; antibodies, negative. Bedside ultrasonography shows macrocephaly with a large calcified central intracranial heterogeneous mass of peculiar vascularity measuring 7.74 × 6.55 × 8.37 cm3 in the midline supratentorial region, replacing brain tissue with thinning of the brain parenchyma. The infratentorial structure is normal and no other...

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