Assisted reproductive technology (ART) techniques have enabled couples with low fertility to conceive, and approximately 1% of births in the United States result from such procedures. ART combined with preimplantation genetic diagnosis (PGD) has provided a method for couples at risk for genetic conditions to deliver a baby free from the condition. ART presents many perinatal risks and may be associated with long-term health effects for the offspring. PGD, which can screen for known conditions, at present cannot screen for all genetic conditions.

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