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Amphotericin B Deoxycholate



Amphotericin B Deoxycholate


(am foe TER i sin bee de ok se KO late)

Therapeutic Category

  • Antifungal Agent, Systemic
  • Antifungal Agent, Topical

Medication Safety Issues

High alert medication:

The Institute for Safe Medication Practices (ISMP) includes this medication among its list of drugs which have a heightened risk of causing significant patient harm when used in error.

Sound-alike/look-alike issues:

Amphotericin B may be confused with amphotericin B liposomal

Other safety concerns:

Conventional amphotericin formulations (deoxycholate [Amphocin, Fungizone]) may be confused with lipid-based formulations (AmBisome, Abelcet, Amphotec).

Large overdoses have occurred when conventional formulations were dispensed inadvertently for lipid-based products. Single daily doses of amphotericin B deoxycholate should not exceed 1.5 mg/kg.

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