Medication Safety Issues
The Institute for Safe Medication Practices (ISMP) includes this medication among its list of drug classes (liposomal forms with conventional counterparts) which have a heightened risk of causing significant patient harm when used in error (High-Alert Medications in Acute Care Settings).
AmBisome may be confused with Ambisolm, Ambisom
Amphotericin B liposomal may be confused with amphotericin B
Lipid-based amphotericin formulations (AmBisome) may be confused with conventional formulations (Amphocin, Fungizone) or with other lipid-based amphotericin formulations (Abelcet, Amphotec)
Large overdoses have occurred when conventional formulations were dispensed inadvertently for lipid-based products. Single daily doses of conventional amphotericin formulation never exceed 1.5 mg/kg.
