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Amphotericin B (Liposomal)

Basics

Name

Amphotericin B (Liposomal)

Pronunciation

(am foe TER i sin bee lye po SO mal)

Brand Names: US

  • AmBisome

Therapeutic Category

  • Antifungal Agent, Systemic

Medication Safety Issues

High alert medication:

The Institute for Safe Medication Practices (ISMP) includes this medication among its list of drugs which have a heightened risk of causing significant patient harm when used in error.

Sound-alike/look-alike issues:

AmBisome may be confused with Ambisolm, Ambisom

Amphotericin B liposomal may be confused with amphotericin B

Other safety concerns:

Lipid-based amphotericin formulations (AmBisome) may be confused with conventional formulations (Amphocin, Fungizone) or with other lipid-based amphotericin formulations (Abelcet, Amphotec)

Large overdoses have occurred when conventional formulations were dispensed inadvertently for lipid-based products. Single daily doses of conventional amphotericin formulation never exceed 1.5 mg/kg.

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