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Tetracycline (Systemic)



Tetracycline (Systemic)


(tet ra SYE kleen)

Therapeutic Category

  • Acne Products
  • Antibiotic, Ophthalmic
  • Antibiotic, Tetracycline Derivative
  • Antibiotic, Topical

Medication Safety Issues

Sound-alike/look-alike issues:

Tetracycline may be confused with tetradecyl sulfate

Achromycin may be confused with actinomycin, Adriamycin

Pediatric patients: High-risk medication:

KIDs List: Tetracycline, when used in neonates, infants, and children <8 years of age, is identified on the Key Potentially Inappropriate Drugs in Pediatrics (KIDs) list. In neonates, tetracycline should be used with caution due to risk of retardation of skeletal development and bone growth in premature neonates (strong recommendation; moderate quality of evidence); in infants and children <8 years of age, it should be used with caution due to risk of tooth discoloration and enamel hypoplasia (strong recommendation; high quality of evidence) (PPA [Meyers 2020]).

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