Therapeutic Category
- Antineoplastic Agent, Camptothecin
- Antineoplastic Agent, Topoisomerase Inhibitor
Medication Safety Issues
Sound-alike/look-alike issues:
Hycamtin may be confused with Mycamine
Topotecan may be confused with irinotecan
High alert medication:
The Institute for Safe Medication Practices (ISMP) includes this medication among its list of drug classes (chemotherapeutic agent, parenteral and oral) which have a heightened risk of causing significant patient harm when used in error (High-Alert Medications in Acute Care, Community/Ambulatory Care, and Long-Term Care Settings).
Other safety concerns:
Topotecan overdoses have been reported; potential causes include omission of the leading zero and missing the decimal point when prescribing, preparing, and administering. Recommended intravenous doses should generally not exceed 4 mg; verify dose prior to administration.