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Alteplase

Basics

Name

Alteplase

Pronunciation

(AL te plase)

Brand Names: US

  • Activase
  • Cathflo Activase

Therapeutic Category

  • Thrombolytic Agent
  • Thrombotic Occlusion (Central Venous Catheter), Treatment Agent

Medication Safety Issues

Sound-alike/look-alike issues:

Activase may be confused with Cathflo Activase, TNKase

Alteplase may be confused with Altace

High alert medication:

The Institute for Safe Medication Practices (ISMP) includes this medication among its list of drug classes (thrombolytic agent) which have a heightened risk of causing significant patient harm when used in error (High-Alert Medications in Acute Care Settings).

Other safety concerns:

TPA, tPA are error-prone abbreviations (mistaken as TNK [TNKase, tenecteplase], TXA [tranexamic acid], another tissue plasmogen activator Retavase [retaplase])

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