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Alteplase

Basics

Name

Alteplase

Pronunciation

(AL te plase)

Brand Names: US

  • Activase
  • Cathflo Activase

Therapeutic Category

  • Thrombolytic Agent
  • Thrombotic Occlusion (Central Venous Catheter), Treatment Agent

Medication Safety Issues

Sound-alike/look-alike issues:

Activase may be confused with Cathflo Activase, TNKase

Alteplase may be confused with Altace

“tPA” abbreviation should not be used when ordering this medication; has been mistaken as TNKase (tenecteplase), TPN (total parenteral nutrition), TXA (error-prone abbreviation for tranexamic acid)

High alert medication:

The Institute for Safe Medication Practices (ISMP) includes this medication (IV) among its list of drugs which have a heightened risk of causing significant patient harm when used in error.

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