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Naloxone

Basics

Name

Naloxone

Pronunciation

(nal OKS one)

Brand Names: US

  • Kloxxado
  • LifEMS Naloxone [DSC]
  • Narcan
  • Narcan [OTC]
  • Rextovy
  • RiVive [OTC]
  • Zimhi

Therapeutic Category

  • Antidote
  • Opioid Antagonist

Medication Safety Issues

Sound-alike/look-alike issues:

Naloxone may be confused with Lanoxin, nalbuphine, naltrexone

Narcan may be confused with Marcaine, Norcuron

Pediatric patients: High-risk medication:

KIDs List: Naloxone, when used in neonates for postpartum resuscitation, is identified on the Key Potentially Inappropriate Drugs in Pediatrics (KIDs) list; use should be avoided due to risk of seizure (strong recommendation; high quality of evidence) (PPA [Meyers 2020]).

International issues:

Narcan [multiple international markets] may be confused with Marcen brand name for ketazolam [Spain]

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