Medication Safety Issues
Sound-alike/look-alike issues:
Topamax may be confused with Sporanox, TEGretol, TEGretol-XR, Toprol-XL
Older Adult: High-Risk Medication:
Topiramate is identified in the Screening Tool of Older Person's Prescriptions (STOPP) criteria as a potentially inappropriate medication in older adults (≥65 years of age) with recurrent falls (O’Mahony 2023).
Administration issues:
Bioequivalence has not been demonstrated between Trokendi XR and Qudexy XR.
Qudexy XR capsules may be swallowed whole or opened to sprinkle the entire contents on a small amount (~1 teaspoon) of soft food. Do not open and sprinkle Trokendi XR capsules on food, chew, or crush; doing so may disrupt the triphasic release properties.
Avoid alcohol use with Trokendi XR within 6 hours prior to and 6 hours after administration; concurrent use may result in dose dumping.