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Levothyroxine

Basics

Name

Levothyroxine

Pronunciation

(lee voe thye ROKS een)

Brand Names: US

  • Ermeza
  • Euthyrox
  • Levoxyl
  • Synthroid
  • Thyquidity
  • Tirosint
  • Tirosint-SOL
  • Unithroid

Therapeutic Category

  • Thyroid Product

Medication Safety Issues

Sound-alike/look-alike issues:

Levothyroxine may be confused with lamoTRIgine, Lanoxin, levoFLOXacin, liothyronine

Levoxyl may be confused with Lanoxin, Levaquin, Luvox

Synthroid may be confused with Symmetrel

Older Adult: High-Risk Medication:

Levothyroxine is identified in the Screening Tool of Older Person's Prescriptions (STOPP) criteria as a potentially inappropriate medication in older adults (≥65 years of age) for the treatment of subclinical hypothyroidism (O’Mahony 2023).

Administration issues:

Oral solutions vary in concentration; consider total dosage in terms of mcg and not volume (mL) when converting between oral solution products.

Significant differences exist between oral and IV dosing. Use caution when converting from one route of administration to another.

Other safety concerns:

To avoid errors due to misinterpretation of a decimal point, always express dosage in mcg (not mg).

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