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Loperamide

Basics

Name

Loperamide

Pronunciation

(loe PER a mide)

Brand Names: US

  • Anti-Diarrheal [OTC]
  • Diamode [OTC]
  • Imodium A-D [OTC]
  • Loperamide A-D [OTC] [DSC]

Therapeutic Category

  • Antidiarrheal

Medication Safety Issues

Sound-alike/look-alike issues:

Imodium A-D may be confused with Indocin

Loperamide may be confused with furosemide, Lomotil

Pediatric patients: High-risk medication:

KIDs List: Loperamide, when used in pediatric patients <2 years of age with acute infectious diarrhea, is identified on the Key Potentially Inappropriate Drugs in Pediatrics (KIDs) list and should be avoided due to risk of ileus and lethargy (strong recommendation; high quality of evidence) (PPA [Meyers 2020]).

International issues:

Indiaral [France] may be confused with Inderal and Inderal LA brand names for propranolol [US, Canada, and multiple international markets]

Lomotil: Brand name for loperamide [Mexico, Philippines], but also the brand name for diphenoxylate [US, Canada, and multiple international markets]

Lomotil [Mexico, Philippines] may be confused with Ludiomil brand name for maprotiline [multiple international markets]

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