Medication Safety Issues
Sound-alike/look-alike issues:
Cyklokapron may be confused with cycloSPORINE
TXA (occasional abbreviation for tranexamic acid) is an error-prone abbreviation (mistaken as TNK an error-prone abbreviation for tenecteplase and tPA an error-prone abbreviation for alteplase)
Administration issues:
Inadvertent administration of tranexamic acid by the epidural or spinal route during neuraxial (eg, epidural, spinal) anesthesia has led to potentially fatal neurotoxic adverse reactions. Carefully evaluate storage procedures within the surgical suite, including separating tranexamic acid from local anesthetics; consider additional prevention measures, including purchasing, dispensing, and administration (ISMP [Smetzer] 2019; NAN Alert 2020; Patel 2019).
