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Scopolamine

Basics

Name

Scopolamine

Pronunciation

(skoe POL a meen)

Brand Names: US

  • Transderm Scop (1.5 MG) [DSC]
  • Transderm-Scop

Therapeutic Category

  • Anticholinergic Agent
  • Anticholinergic Agent, Transdermal

Medication Safety Issues

Older Adult: High-Risk Medication:

Beers Criteria: Scopolamine is identified in the Beers Criteria as a potentially inappropriate medication to be avoided in patients 65 years and older (independent of diagnosis or condition) due to its highly anticholinergic properties and uncertain effectiveness as an antispasmodic (Beers Criteria [AGS 2023]).

Scopolamine is identified in the Screening Tool of Older Person's Prescriptions (STOPP) criteria as a potentially inappropriate medication in older adults (≥65 years of age) for lower urinary tract symptoms with benign prostatic hyperplasia (BPH) and high post-void residual volume, ie, >200 mL. Some disease states of concern include delirium, dementia, chronic cognitive impairment, narrow-angle glaucoma, overactive bladder, urge incontinence, and chronic constipation (O’Mahony 2023).

Other safety concerns:

Transdermal patch may contain conducting metal (eg, aluminum); remove patch prior to MRI.

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