Skip to Main Content
Skip Nav Destination






(TEK oh VIR i mat)

Brand Names: US

  • Tpoxx

Therapeutic Category

  • Antiviral Agent

Generic Availability (US)


Index Terms

  • Tpoxx, ST-246

Clinical Pharmacology

Mechanism of Action

Tecovirimat inhibits the activity of the orthopoxvirus VP37 protein and blocks its interaction with cellular Rab9 GTPase and TIP47, preventing formation of egress-competent enveloped virions (necessary for dissemination of virus).

This item requires a subscription. For full access to this content, please log in to an existing user account or purchase an individual subscription. If you have an active subscription and appear logged in (your name appears in the upper right corner), but you cannot access content, please click the “Log Out” option under your name and log back in.
Close Modal

or Create an Account

Close Modal
Close Modal