Perry T, Matsui E, Merriman B, Duong T, Eggleston P. J Allergy Clin Immunol. 2003;112:346–352
To determine the prevalence of rat allergen in the homes of inner-city children with asthma and to examine the relationship between rat allergen exposure, sensitization, and asthma morbidity
Children enrolled in the National Cooperative Inner-City Asthma Study were studied.
Dust samples collected from the homes of 1528 asthmatic children from 8 major inner-city areas were analyzed with the use of a new monoclonal antibody-based enzyme-linked immunosorbent assay, to determine the prevalence of rat allergen in dust samples from inner-city homes of the National Cooperative Inner-City Asthma Study population. Home characteristics were evaluated to identify variables that were associated with the presence of rat allergen. Data were also analyzed to assess the relationships between the presence of rat allergen, sensitization, and asthma morbidity.
Thirty-three percent of inner-city homes had detectable rat allergen (Rat n 1)....