Korppi M, Hyvärinen M, Kotaniemi-Syrjänen A, Piippo-Savolainen E, Reijonen T. Pediatr Allergy Immunol. 2008;19(8):696–701

PURPOSE OF THE STUDY. Birth cohort studies have suggested that early exposure to furred pets protects from later asthma and allergy. The aim of this study was to evaluate the association between exposure or sensitization to cat or dog in infancy and later asthma and allergy assessed at the median ages of 4.0, 7.2, and 12.3 years.

STUDY POPULATION. Children 1 to 23 months of age who had wheezing and respiratory distress that required hospital care during an acute respiratory tract infection were enrolled.

METHODS. Exposure to cat and dog in infancy was assessed by interviewing the parents. The child was considered to be sensitized if the allergen-specific immunoglobulin E level to cat or dog was ≥0.35 kU/L or if there was a positive skin-test response.

RESULTS. When the 20 children with persistent childhood asthma (doctor-diagnosed...

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