The relation between smoke exposure in early life, the prenatal period in particular, and the vascular development of young children is largely unknown.
Data from the birth cohort participating in the WHISTLER-Cardio study were used to relate the smoking of parents during pregnancy to subsequent vascular properties in their children. In 259 participating children who turned 5 years of age, parental smoking data were updated and children’s carotid artery intima-media thickness (CIMT) and arterial wall distensibility were measured by using ultrasonography.
Children of mothers who had smoked throughout pregnancy had 18.8 μm thicker CIMT (95% confidence interval [CI] 1.1, 36.5, P = .04) and 15% lower distensibility (95% CI −0.3, −0.02, P = .02) after adjustment for child’s age, maternal age, gender, and breastfeeding. The associations were not found in children of mothers who had not smoked in pregnancy but had smoked thereafter. The associations were strongest if both parents had smoked during pregnancy, with 27.7 μm thicker CIMT (95% CI 0.2, 55.3) and 21% lower distensibility (95% CI −0.4, −0.03).
Exposure of children to parental tobacco smoke during pregnancy affects their arterial structure and function in early life.
Comments
"Smoking", Dioxin, and Vascular Problems
A troubling aspect of this study is that, by ignoring the presence of chlorine pesticide residues and chlorine-bleached cigarette paper, the study further ignores volumes of past studies about dioxin (that deadly by -product of chlorine) linked to or causing vascular disease.
One needs only to search up relevant terms to see the highly relevant, integral material. Try "dioxin cigarette smoke", or "pesticides tobacco" or "GAO tobacco pesticides", or "EPA chlorine dioxin" or "dioxin vascular", "pesticides vascular" or similar terms. If the researchers did such a search, the results didn't make it into their conclusions...and parents, their children, and all those who believe and are still told their cigarettes are tobacco or just tobacco remain endangered, and uncompensated, due to failure by medical science to inform and protect.
Since tobacco, according to the GAO, is the Sixth Most Pesticide Intensive Crop, it is inconceivable...certainly unacceptable...that pesticides are routinely left out of studies of smoking and health.
If typical cigarettes were more helpfully called "Pesticide Pegs" or "Dioxin Dowels", instead of just "coffin nails" or whatnot, the health advantages would be historic and global.
Conflict of Interest:
None declared