The amount of alveolar rupture and hemorrhage resulting from artificial respiration tion is dependent not only upon the degree of pressure and the time it is applied but also on the proportion of total lung volume that is expansible. The danger of such rupture is greater for a given pressure change, the greater the amount of unexpansible lung. The amount of atelectasis, pulmonary congestion or obstruction that prevents expansion of lung is clinically not quantitatively measurable, so that no exact rule for time and pressures can be established that will be completely safe.

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