Autism spectrum disorders (ASDs) are a set of complex neurodevelopmental disorders defined behaviorally by impaired social interaction, delayed and disordered language, repetitive or stereotypic behavior, and a restricted range of interests. ASDs represent a significant public health issue with recent estimates indicating that as many as 1% of children in the United States are diagnosed with an ASD.1,2 Many individuals with ASDs have symptoms of associated medical conditions, including seizures, sleep problems, metabolic conditions, and gastrointestinal (GI) disorders, which have significant health, developmental, social, and educational impacts. Gastrointestinal complaints are a commonly reported concern for parents and may be related to problem behaviors and other medical issues such as dysregulated sleep (ATN Annual Registry Report, unpublished data, November 2009).3 Despite the magnitude of these issues, potential GI problems are not routinely considered in ASD evaluations. This likely reflects several factors, including variability in reported rates of...
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November 2012
Supplement Articles|
November 01 2012
Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda
Daniel L. Coury, MD;
aDevelopmental/Behavioral Pediatrics, Nationwide Children’s Hospital, Columbus, Ohio;
Address correspondence to Daniel L. Coury, MD, Professor of Pediatrics and Psychiatry, The Ohio State University, Chief, Developmental & Behavioral Pediatrics, Nationwide Children's Hospital, 700 Children's Dr, Timken G-350, Columbus OH 43205-2696
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Paul Ashwood, PhD;
Paul Ashwood, PhD
bDepartment of Medical Microbiology and Immunology, University of California, Davis, Davis, California;
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Alessio Fasano, MD;
Alessio Fasano, MD
cPediatrics, University of Maryland, School of Medicine, Baltimore, Maryland;
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George Fuchs, MD;
George Fuchs, MD
dPediatrics/Pediatric Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, Arkansas;
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Maureen Geraghty, PhD;
Maureen Geraghty, PhD
eMedical Dietetics, Abbott Laboratories, Columbus, Ohio;
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Ajay Kaul, MBBS;
Ajay Kaul, MBBS
fPediatrics, Cincinnati Children’s Hospital, Cincinnati, Ohio;
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Gary Mawe, PhD;
Gary Mawe, PhD
gAnatomy and Neurobiology, University of Vermont, Burlington, Vermont;
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Paul Patterson, PhD;
Paul Patterson, PhD
hCalifornia Institute of Technology, Pasadena, California; and
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Nancy E. Jones, PhD
Nancy E. Jones, PhD
iClinical Programs, Autism Speaks, Los Angeles, California
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Address correspondence to Daniel L. Coury, MD, Professor of Pediatrics and Psychiatry, The Ohio State University, Chief, Developmental & Behavioral Pediatrics, Nationwide Children's Hospital, 700 Children's Dr, Timken G-350, Columbus OH 43205-2696
Pediatrics (2012) 130 (Supplement_2): S160–S168.
Article history
Accepted:
August 08 2012
Citation
Daniel L. Coury, Paul Ashwood, Alessio Fasano, George Fuchs, Maureen Geraghty, Ajay Kaul, Gary Mawe, Paul Patterson, Nancy E. Jones; Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda. Pediatrics November 2012; 130 (Supplement_2): S160–S168. 10.1542/peds.2012-0900N
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