A prenatal diagnosis of ductal-dependent, complex congenital heart disease was made in a fetus with trisomy 18. The parents requested that the genetic diagnosis be excluded from all medical and surgical decision-making and that all life-prolonging therapies be made available to their infant. There was conflict among the medical team about what threshold of neonatal benefit could outweigh maternal and neonatal treatment burdens. A prenatal ethics consultation was requested.
Trisomy 18 and Complex Congenital Heart Disease: Seeking the Threshold Benefit
FINANCIAL DISCLOSURE: The authors have indicated they have no financial relationships relevant to this article to disclose.
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Renee D. Boss, Kathryn W. Holmes, Janyne Althaus, Cynda H. Rushton, Hunter McNee, Theresa McNee; Trisomy 18 and Complex Congenital Heart Disease: Seeking the Threshold Benefit. Pediatrics July 2013; 132 (1): 161–165. 10.1542/peds.2012-3643
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